亚瑟（凯德·麦拉德 Kad Merad 饰）遭到相恋五年女友的突然劈腿，难以接受事实的他决定远赴千里赶往迈阿密阻止她的婚电影天堂。不料在机场阴差阳错的被女飞贼艾米丽（梅兰妮·杜迪 Mélanie Doutey 饰）缠上，艾米丽身怀绝技、专偷名画的女贼艾米丽盗走了一幅价值不菲的名画，为了躲避警察的搜查，将偷取的名画放入了亚瑟的行李包中。一路上艾米丽千方百计想取回名画，却一路被跟踪而来的警察扰乱计划，无辜的亚瑟也被误认为是同伙，阻止前女友婚礼的计划眼看要泡汤，“绝顶”衰男亚瑟不得不与绝色神偷共同进退，一路浪漫逃亡。

80sAstridNielsen,worksinthelibraryofthejudicialpolice.SufferingfromAsperger’ssyndrome,however,shehasanincrediblememory,sosheisveryusefulinanalyzingthefilesforongoinginvestigations.Thedistrictcommander,havingnoticedthisability,decidestouseittothefullest,entrustingherwithverycomplexinvestigationswhichhaveremainedunsolvedtodate.Inaddition,alsotoreciprocate,hewilltrytohelpAstridonthebehavioralside,inordertoprovidemutualhelp.

80s　Astrid Nielsen, works in the library of the judicial police. Suffering from Asperger's syndrome, however, she has an incredible memory, so she is very useful in analyzing the files for ongoing investigations. The district commander, having noticed this ability, decides to use it to the fullest, entrusting her with very complex investigations which have remained unsolved to date. In addition, also to reciprocate, he will try to help Astrid on the behavioral side, in order to provide mutual help.